Essentials+
- $748.00
- $598.40
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FSA / HSA eligible
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CHECKOUTResults: 1 to 5 days
Collection: 1 blood draw
Biomarkers: 91
Gender: unisex
Coverage: full-body
Essentials+ is an all-in-one early detection diagnostic panel. Analyzing 91 foundational biomarkers across 11 health domains, it’s capable of detecting patterns of inflammation, dysfunction, and disease years before physical symptoms appear
1 all-inclusive test
91 foundational biomarkers
11 health domains
360 degree coverage
Completed labs are automatically posted to your MyQuest account — samples can be submitted at any Quest Patient Service Center nationwide.
After establishing a baseline, retest every six months to monitor progress and reassess health status.
Popular add-ons: Hormone Health, Allergy Profile
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Essentials+ includes the following tests, covering 91 biomarkers:
Aluminum
- tested biomarkers: 1
- result availability: 3 to 4 days
Apolipoprotein B
- tested biomarkers: 1
- result availability: 3 to 4 days
C-Peptide
- tested biomarkers: 1
- result availability: 1 to 2 days
Complete Blood Count (CBC)
- includes differential and platelets
- tested biomarkers: 33
- results availability: 1 to 2 days
Comprehensive Metabolic Panel (CMP)
- tested biomarkers: 21
- results availability: 1 to 2 days
Cortisol, Total
- tested biomarkers: 1
- result availability: 1 to 2 days
Cystatin C with eGFR
- tested biomarkers: 2
- results availability: 3 to 4 days
Ferritin
- tested biomarkers: 1
- result availability: 1 to 2 days
Gamma Glutamyl Transferase (GGT)
- tested biomarkers: 1
- result availability: 1 to 2 days
Hemoglobin A1c (HgbA1C)
- tested biomarkers: 1
- result availability: 1 to 2 days
HOMA IR (Insulin Resistance)
- tested biomarkers: 2
- result availability: 2 to 3 days
Homocysteine
- tested biomarkers: 1
- result availability: 2 to 3 days
hs CRP
- tested biomarkers: 1
- result availability: 2 to 3 days
Immunoglobulin G (IgG)
- tested biomarkers: 1
- result availability: 2 to 3 days
Insulin
- tested biomarkers: 1
- result availability: 2 to 3 days
Iron, Total
- tested biomarkers: 1
- result availability: 1 to 2 days
Total Iron Binding Capacity (TIBC)
- tested biomarkers: 1
- result availability: 1 to 2 days
% Saturation
- tested biomarkers: 1
- result availability: 1 to 2 days
Lipase
- tested biomarkers: 1
- result availability: 1 to 2 days
Lipid Panel
- tested biomarkers: 6
- result availability: 1 to 2 days
Magnesium
- tested biomarkers: 1
- result availability: 1 to 2 days
Phosphate (as Phosphorus)
- tested biomarkers: 1
- result availability: 1 to 2 days
PTH (Parathyroid Hormone), Intact (without Calcium)
- tested biomarkers: 1
- result availability: 1 to 2 days
T3, Free
- tested biomarkers: 1
- result availability: 1 to 2 days
T4, Free
- tested biomarkers: 1
- result availability: 1 to 2 days
Thyroid Stimulating Hormone (TSH)
- tested biomarkers: 1
- result availability: 1 to 2 days
Uric Acid
- tested biomarkers: 1
- result availability: 1 to 2 days
Vitamin A (Retinol)
- tested biomarkers: 1
- result availability: 4 to 5 days
Vitamin B12 (Cobalamin) and Folate Panel, Serum
- tested biomarkers: 2
- results availability: 1 to 2 days
Vitamin D, 25-Hydroxy, Total, Immunoassay
- tested biomarkers: 1
- result availability: 1 to 2 days
Vitamin E (Tocopherol)
- tested biomarkers: 2
- results availability: 4 to 5 days
Zinc
- tested biomarkers: 1
- result availability: 4 to 5 days
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Essentials+ is 11 diagnostic panels in 1:
Bone Health
Cardiovascular Health
Glycemic Health
Immune Function
Iron Balance
Kidney Function
Liver Function
Metabolic Health
Nutrient Balance
Thyroid Function
Biological Age
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Bone Health diagnostic panel assesses the integrity, density and metabolic activity of the skeletal system. Optimal bone health is contingent on the balanced interplay between the following biomarkers:
Magnesium (mg/dL): essential for converting vitamin D into its active form and regulating calcium transport.
Phosphate (as Phosphorus) (mg/dL): works with calcium to build strong bones and teeth; imbalances can weaken bone integrity.
Parathyroid Hormone (pg/mL): PTH regulates calcium and phosphate levels; elevated PTH may indicate bone loss or imbalance.
Vitamin D (ng/mL): crucial for calcium absorption and bone mineralization; deficiency is a major risk factor for osteoporosis.
Calcium (mg/dL): core mineral in bone structure; low levels may signal poor bone density or absorption issues.
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Cardiovascular Health diagnostic panel assesses the performance of the circulatory system, examining key markers of vascular function, lipid metabolism, and cardiac stress. Optimal cardiovascular health is contingent on the balanced interplay between the following biomarkers:
Apolipoprotein B (mg/dL): the most accurate marker of atherogenic particle count.
Hgb A1c (%): reveals average blood sugar levels over time; high levels increase risk of heart disease.
hs CRP (mg/L): detects low-grade inflammation in arteries—a hidden driver of atherosclerosis and cardiovascular events.
Lipoprotein (A) (nmol/L): elevated levels of Lp(a) are a risk factor for cardiovascular disease, heart attacks, strokes, aortic valve disease, and heart failure.
Hematocrit (%): proportion of blood made up of red cells; impacts blood viscosity and circulation efficiency.
Hemoglobin (g/dL): carries oxygen in the blood; low levels can signal anemia, limiting oxygen supply to the heart.
LDL-Cholesterol (mg/dL): reflects concentration of cholesterol carried by LDL particles, a key driver of atherosclerosis.
Red Blood Cell Count (million/uL): vital for oxygen delivery; too high or low may strain cardiovascular function.
RDW (%): red cell distribution width measures variation in RBC size; elevated RDW is linked to inflammation and increased cardiovascular risk.
Triglycerides (mg/dL): reveal metabolic health and insulin sensitivity—essential for assessing long-term cardiovascular risk.
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Glycemic health diagnostic panel assesses the efficiency with which the body maintains glucose homeostasis, focusing on key factors such as insulin sensitivity and metabolic resilience. Optimal glycemic health is contingent on the balanced interplay between the following biomarkers:
Cortisol (mcg/dL): chronically elevated levels disrupt blood sugar control and increase insulin resistance.
C-Peptide (ng/mL): reflects how much insulin your pancreas is producing — key to assessing insulin reserve and beta cell function.
Hemoglobin A1c (%): shows your 3-month average blood glucose; high A1c points to chronic glucose elevation.
HOMA-IR (unitless): estimates insulin resistance using fasting insulin and glucose levels as inputs.
Insulin (mIU/L): the hormone that lowers blood sugar by moving glucose into cells; elevated fasting insulin suggests insulin resistance.
Lipase (U/L): an enzyme made by the pancreas; high levels may signal pancreatic stress, which can affect insulin production.
Uric Acid (mg/dL): excess levels are linked to metabolic syndrome, insulin resistance, and increased risk of type 2 diabetes.
Glucose (mg/dL): your real-time blood sugar level; critical for detecting hypoglycemia, prediabetes, or diabetes.
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Immune function: a strong immune system requires a balance between activation and regulation—too weak, and we succumb to infections; too strong, and we face autoimmunity. Optimal immune function is contingent on the balanced interplay between the following biomarkers:
Ferritin (ng/mL): primary iron storage protein; low levels can weaken immune defenses, while high levels may signal inflammation.
hs CRP (mg/L): highly sensitive marker of hidden inflammation; elevated levels can indicate chronic immune activation or infection.
Immunoglobulin G (mg/dL): IgG is the most abundant antibody; key to long-term immune memory and defense against recurring infections.
Vitamin D (ng/mL): crucial for immune modulation; deficiency is linked to increased susceptibility to infection and autoimmune conditions.
Absolute Eosinophils (cells/uL): specialized cells involved in allergy and parasite defense; elevated levels can suggest allergic or autoimmune activity.
Absolute Lymphocytes (cells/uL): vital for adaptive immunity and viral defense; abnormal levels may reflect viral infections or chronic immune stress.
Absolute Neutrophils (cells/uL): frontline defenders against bacterial infections; elevated levels typically indicate acute immune response.
White Blood Cells Count (K/uL): overall measure of immune activity; high or low counts can signal infection, inflammation, or immune suppression.
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Iron balance: iron is an essential mineral responsible for oxygen transport, energy production, and immune function. Iron dysfunction is often silent until the condition becomes critical. Optimal iron balance is contingent on the balanced interplay between the following biomarkers:
Ferritin (ng/mL): primary iron storage protein; low levels suggest deficiency, high levels may indicate inflammation or overload.
Iron, Total (mcg/dL): measures circulating iron; reflects how much iron is immediately available for use in the body.
Total Iron Binding Capacity (mcg/dL): TIBC measures the blood’s capacity to transport iron; elevated levels can signal iron deficiency.
% Saturation (%): indicates how much of the transport protein (transferrin) is bound to iron; low saturation often confirms deficiency.
Hematocrit (%): percentage of blood composed of red cells; used alongside hemoglobin.
Hemoglobin (g/dL): iron-containing protein in red blood cells; essential for oxygen transport—low levels indicate anemia.
MCV (fL): mean corpuscular volume measures the average size of red blood cells; low values point to iron-deficiency anemia.
RDW (%): red cell distribution width assesses variability in red blood cell size; elevated RDW can indicate early iron deficiency or chronic blood loss.
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Kidney function: kidneys are the body’s purification system, quietly removing toxins, balancing minerals, and keeping the body in homeostasis. Early kidney disease is often invisible, until the condition becomes serious. Optimal kidney function is contingent on the balanced interplay between the following biomarkers:
Aluminum (mcg/L): neurotoxic metal cleared by the kidneys; elevated levels may indicate poor detox function or exposure overload.
Cystatin C (mg/L): sensitive marker of kidney filtration function; often more accurate than creatinine, especially in early dysfunction.
eGFR (mL/min): estimates how well your kidneys are filtering blood; the gold standard for staging kidney disease.
Blood Urea Nitrogen (mg/dL): reflects waste buildup in the blood; elevated levels may suggest impaired kidney clearance.
BUN/Creatinine Ratio (calculated): helps distinguish between kidney and non-kidney causes of elevated BUN or creatinine.
Creatinine (mg/dL): byproduct of muscle metabolism; high levels indicate reduced kidney function or dehydration.
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Liver function diagnostic panel measures enzymes, proteins, and metabolic byproducts that reflect hepatic performance and integrity. Liver health is essential, as nearly all the blood that leaves the stomach and intestines passes through the liver for processing. Optimal liver function is contingent on the balanced interplay between the following biomarkers:
GGT (U/L): Gamma-Glutamyl Transferase enzyme is an early warning signal of liver stress, alcohol use, or toxin overload.
ALT (U/L): Alanine aminotransferase is a key enzyme released when liver cells are damaged; a frontline marker of liver injury.
Albumin (g/dL): main blood protein made by the liver; low levels suggest impaired liver function or chronic disease.
Alkaline Phosphatase (U/L): used to detect bile duct issues and liver congestion; also relevant for bone health.
AST (U/L): elevated levels of this enzyme may point to liver inflammation or muscle injury.
Bilirubin (mg/dL): pigment formed during red blood cell breakdown; high levels may indicate blocked bile flow or liver dysfunction.
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Metabolic health: metabolic health is achieved when multiple systems — including endocrine, cardiovascular, hepatic, and renal — are functioning in harmony to maintain stable energy production, nutrient transport, and inflammation control. Optimal metabolic health is contingent on the balanced interplay between the following biomarkers:
Apolipoprotein B (mg/dL): best-in-class marker of harmful LDL particle count—strong predictor of heart and metabolic disease.
C-Peptide (ng/mL): indicates how much insulin your body is producing naturally—key for diagnosing insulin resistance.
GGT (U/L): Gamma-Glutamyl Transferase is a sensitive liver enzyme linked to oxidative stress, insulin resistance, and toxic overload.
Hemoglobin A1c (%): 3-month average of blood sugar; high levels indicate poor glucose control and risk of diabetes.
HOMA IR (unitless): integrates glucose + insulin to estimate insulin resistance—the silent root of many chronic conditions.
Homocysteine (umol/L): a byproduct of metabolism; elevated levels increase risk of cardiovascular and neurological disorders.
hs CRP (mg/L): high-sensitivity C-reactive protein detects hidden inflammation driving insulin resistance and chronic disease.
Insulin (mIU/L): elevated insulin signals early metabolic dysfunction—often years before blood sugar rises.
T4, Free (ng/dL): thyroid hormone regulating metabolic rate and energy production; low levels can slow metabolism.
Uric Acid (mg/dL): linked to poor metabolic health, gout, and cardiovascular risk; high levels correlate with insulin resistance.
ALT (U/L): Alanine aminotransferase is a liver enzyme elevated in fatty liver and metabolic syndrome—early signal of metabolic damage.
Glucose (mg/dL): snapshot of current blood sugar levels—essential for diagnosing prediabetes and diabetes.
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Nutrient balance: vitamins and minerals play an essential role in metabolism, immune function, brain health, and cellular repair. Nutrient balance diagnostic panel detects deficiencies and imbalances impairing metabolic pathways. Optimal nutrient balance is contingent on the balanced interplay between the following biomarkers:
Homocysteine (umol/L): requires B vitamins (B6, B9, B12) to break down properly; elevated levels signal deficiency and increased cardiovascular risk.
Magnesium (mg/dL): vital for over 300 enzymatic reactions, including muscle function, energy production, and blood sugar control.
Vitamin A (Retinol) (mcg/dL): essential for vision, immune defense, and skin health; deficiency can impair cell growth and repair.
Vitamin B12 (pg/mL): crucial for nerve function, red blood cell production, and DNA synthesis; low levels may cause fatigue and neurological issues.
Folate (ng/mL): folate, also known as Vitamin B9, supports cell division, DNA repair, and brain development; deficiency linked to anemia and neural defects.
Vitamin D (ng/mL): regulates calcium absorption, immune modulation, and inflammation control; low levels are widespread and tied to chronic illness.
Vitamin E, Alpha T (mg/L): powerful antioxidant that protects cells from oxidative stress; supports skin, heart, and immune health.
Zinc (mcg/dL): supports immune defense, wound healing, and cellular repair; deficiency impacts hormonal and metabolic function.
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Thyroid function: the thyroid gland is the master regulator of metabolism, energy, and hormonal balance. Thyroid disfunction can profoundly influence weight, mood, cognitive function, and cardiovascular risk. Optimal thyroid function is contingent on the balanced interplay between the following biomarkers:
T3, Free (pg/mL): the active thyroid hormone that regulates metabolism, energy, and body temperature; low levels often indicate underactive thyroid.
T4, Free (ng/dL): the storage form of thyroid hormone, converted to T3 in tissues; reflects the thyroid’s production capacity.
TSH (mIU/L): Thyroid Stimulating Hormone is produced by the pituitary gland to signal the thyroid; elevated TSH usually means the thyroid is underperforming.
Cortisol (mcg/dL): cortisol and thyroid hormones are deeply intertwined. Chronic stress or adrenal dysfunction can block T4-to-T3 conversion and raise reverse T3.
Ferritin (ng/mL): iron is essential for the conversion of T4 to T3 (via deiodinase enzymes). Even suboptimal ferritin (<50 ng/mL) can impair thyroid efficiency.
Vitamin D (ng/mL): vitamin D plays a key role in immune modulation. Low vitamin D is strongly associated with autoimmune thyroid disorders (e.g., Hashimoto’s).
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Biological age measures the velocity of aging — chronological age measures the passage of time. Bio-age has been shown to consistently outperform chronological age as a predictor of physical dysfunction, disease onset, and overall mortality. Biological age is calculated based on levels of the following biomarkers:
Albumin (g/dL) is a protein made by the liver that helps maintain fluid balance, and the efficient transport hormones, vitamins, and drugs. In the Bio-Age model, higher albumin reflects better overall health and lower inflammation, while low levels can signal frailty or chronic illness [optimal range: 3.8–4.5 g/dL].
Creatinine (mg/dL) is a waste product from muscle metabolism and indicates how well the kidneys are filtering blood. In the Bio-Age model, elevated creatinine levels suggest reduced kidney function and accelerated biological aging [optimal range: 0.6–1.1 mg/dL (women) / 0.7–1.3 mg/dL (men)].
Glucose (mg/dL) measures the amount of sugar circulating in the blood, providing insight into how well the body manages energy. In the Bio-Age model, elevated glucose raises biological age because it signals insulin resistance and metabolic dysfunction [optimal range: 70–99 mg/dL].
Insulin (uIU/mL) is the hormone that moves glucose from your blood into cells for energy. In the Bio-Age model, stable, lower insulin levels indicate good metabolic health, while chronically elevated levels point to accelerated metabolic aging [optimal range: 2 - 6 µIU/mL]
hs CRP (mg/L) measures low-grade inflammation in the body and rises when the immune system is stressed and activated. In the Bio-Age model, lower hs CRP values signal lower inflammation and slower biological aging [optimal range: < 1.0 mg/L]
Lymphocytes (%) are white blood cells that help fight infection and support immune memory. In the Bio-Age model, lymphocytes levels outside the optimal range may indicate immune stress or chronic disease [optimal range: 20–40% of total white blood cells].
MCV (fL) measures the average size of red blood cells, helping to identify nutrient status and blood health. In the Bio-Age model, MCV levels outside the optimal range can indicate anemia, nutrient deficiencies (B12, folate), or chronic inflammation [optimal range: 82–97 fL].
RDW (%) shows the variation in size among red blood cells, indicating how efficiently the body produces them. In the Bio-Age model, lower RDW is linked to better longevity and cellular stability, while elevated levels predict accelerated aging [optimal range: 11.5–13.5%]
Alkaline Phosphatase (U/L) is an enzyme found in the liver, bones, and digestive system that reflects metabolic and liver-bone health. In the Bio-Age model, moderate ALP levels indicate balanced metabolism, while elevated levels may reflect tissue inflammation and stress [optimal range: 35–104 U/L].
While Blood Cell Count (K/uL) counts the total number of immune cells circulating in the blood, reflecting how the body responds to stress, inflammation and infection. In the Bio-Age model, elevated WBC levels are linked with inflammation and accelerated biological aging [optimal range: 4.0–8.0 K/uL].