Metabolic Health

$306.00

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Results: 1 to 3 days

Collection: blood draw

Biomarkers: 12

Metabolism refers to all the biochemical reactions and processes your body uses to convert food into energy, build and repair cells, and keep every system running — from your brain to your muscles to your hormones.

Metabolic health is a state in which multiple systems — endocrine, cardiovascular, hepatic, and renal — are functioning in harmony to maintain stable energy production, nutrient transport, and inflammation control.

How to order: all Metabolic Health tests are included as part of The Essentials+ BioMap. A stand-alone Metabolic Health panel is not for sale at this time.

BioMap included tests are listed below.

    • Reference range: <90 mg/dL (above 129 is high risk)

    • Optimal range: <80 (60–80 is great)

    • ApoB (Apolipoprotein B) carries LDL cholesterol and other potentially harmful lipid particles around the body.

    • It includes all cholesterol particles that can form plaque in your arteries and lead to cardiovascular disease.

    • Levels of ApoB can identify risk of cardiovascular disease, even if traditional LDL cholesterol levels are normal.

    • Reference range: <3 mg/L (lower is better)

    • Optimal range: <1

    • hs-CRP (high-sensitivity C-reactive protein) is a biomarker produced by your liver in response to inflammation.

    • ‘High-sensitivity’ refers to the lab test’s ability to detect very low levels of CRP in your blood — low enough to catch hidden or chronic inflammation that traditional CRP tests might miss.

    • Even with normal cholesterol and blood pressure, elevated hs-CRP levels can indicate hidden inflammation, which plays a critical role in plaque buildup, as well as heart attack and stroke risk.

    • The hs-CRP biomarker is also tested as part of the Cardiovascular Health and Immune Response BioMaps.

    • Reference range: <11.4 umol/L

    • Optimal range (male/female): <7.0 / <9.0

    • Homocysteine is an amino acid involved in protein metabolism.

    • It’s an important marker for methylation status, cardiovascular risk, and inflammation.

    • When methylation is suboptimal, homocysteine accumulates, increasing oxidative stress, vascular damage, and cognitive risk.

    • Homocysteine (a byproduct of methylation) is increased by functional deficiency of Vitamin B12 or Folate (Vitamin B9).

    • Methylation is a biochemical process in which your body adds a small chemical group — called a methyl group (one carbon and three hydrogens: CH₃) — to another molecule. This might sound small, but methylation controls some of the most vital processes in your body. Think of methylation as a master switchboard—when the process is underactive or imbalanced, key systems (cardiovascular, neurological, immune, hormonal) can suffer.

    • Reference range: 0.8–1.8 ng/dL

    • Optimal range: 1.0–1.5

    • T4 (thyroxine) is a hormone produced by the thyroid gland.

    • T4 is considered to be a prohormone, as it has minimal biological activity on its own.

    • The body converts T4 into T3 (triiodothyronine), the active form, primarily in the liver, kidneys, and other tissues.

    • T3 binds to nuclear receptors and directly regulates metabolism, temperature, energy, and more.

    • Free T4 is crucial for understanding how much thyroid hormone is available for conversion to T3.

    • Reference range: 3–55 U/L (lower is better)

    • Optimal range: <15

    • GGT (Gamma-Glutamyl Transferase) is one of the first enzymes to rise in response to liver damage.

    • It’s an invaluable early-warning signal, as many liver diseases develop slowly and silently, potentially leading to irreversible damage.

    • How important is the liver? Nearly all the blood that leaves the stomach and intestines passes through the liver for processing.

    • Reference Range: 9-46 U/L

    • Alanine aminotransferase (ALT) is an enzyme produced primarily in the liver, skeletal and heart muscle.

    • ALT is present in the liver in a higher concentration than AST and is more specific for differentiating liver injury from muscle damage.

    • ALT rises in the instance of liver disease.

    • Reference range: <5.7% of total Hgb

    • Optimal range: <5.2%

    • Hgb A1c (Hemoglobin A1c) is a marker of average blood sugar levels over the past 2–3 months.

    • It reflects how much sugar is attached to your red blood cells, offering a long-term view of glucose control.

    • Reference range: 0.80-3.85 ng/mL

    • Optimal range: 0.5–2.0

    • C-peptide is produced in the pancreas at the same time as insulin. However, it stays in the blood longer than insulin does. This makes c-peptide a good indicator of how much insulin is being produced.

    • High levels of c-peptide along with high levels of insulin point to insulin resistance.

    • Reference range: <18.4 uIU/mL

    • Optimal range: <6

    • The blood level of glucose is tightly controlled by hormones, especially insulin, which is produced by the pancreas.

    • In people with diabetes, insulin is either less effective (Type 2) or not produced in sufficient quantity (Type 1), thus making it harder to manage the amount of sugar passing through the blood.

    • Reference range: 65-99 mg/dL

    • Optimal range: 70–85

    • Glucose (“blood sugar”) is the chief source of energy for all cells in the body.

    • Glucose levels are regulated by hormones produced by your pancreas, including insulin.

    • Glucose level outside the optimal range could be a sign of hypoglycemia (low blood sugar), prediabetes (elevated blood sugar), or diabetes (high blood sugar).

    • Optimal range: <1.0 = excellent insulin sensitivity

    • HOMA IR is a derived (calculated) index of insulin resistance. It is the most widely used such index derived from glycemic markers.

    • HOMA-IR Formula = [Fasting Insulin(μIU/mL) × Fasting Glucose(mg/dL)​] / 405

    • If Fasting Insulin = 3.9 µIU/mL

    • If Fasting Glucose: 96 mg/dL

    • Then HOMA IR = .92 = [(3.9 * 96) / 405]

    • Reference range: 2.5–8.0 mg/dL

    • Optimal range (male / female): ≤ 5.5 / ≤ 5.0

    • Uric acid is a waste product created when the body breaks down purines, which are found in DNA, certain foods (e.g., red meat, shellfish, alcohol), and cellular turnover. It’s typically filtered out by the kidneys and excreted in urine.

    • In longevity medicine elevated uric acid is a red flag for early metabolic disturbance, even before glucose or insulin become abnormal.

    • Elevated uric acid is strongly associated with insulin resistance, hypertension, cardiovascular disease, and non-alcoholic fatty liver disease (NAFLD).